Warnings


What may interact with BIJUVA?

Do not take this medicine with any of the following medications:

-aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone
This medicine may also interact with the following medications:

-barbiturates, such as phenobarbital
-bexarotene
-bosentan
-carbamazepine
-certain antibiotics like erythromycin and clarithromycin
-certain medicines for fungal infections like ketoconazole, itraconazole
-certain medicines for hepatitis, HIV or AIDS
-certain medicines for anxiety or sleep
-cyclosporine
-dantrolene
-ethotoin
-grapefruit juice
-griseofulvin
-isoniazid (INH)
-medications for diabetes
-phenobarbital
-phenytoin
-primidone
-raloxifene
-rifabutin
-rifampin
-rifapentine
-ritonavir
-St. John''s Wort
-steroid medicines like prednisone or cortisone
-tamoxifen
-thyroid hormones
-topiramate
-warfarin

What should I tell my health care provider before I take BIJUVA?

They need to know if you have any of these conditions:

-blood vessel disease or blood clots
-breast, cervical, endometrial, or uterine cancer
-diabetes
-endometriosis
-fibroids
-gallbladder disease
-heart disease or recent heart attack
-high blood cholesterol
-high blood pressure
-high level of calcium in the blood
-hysterectomy
-kidney disease
-liver disease
-mental depression
-migraine headaches
-porphyria
-protein C deficiency
-protein S deficiency
-stroke
-systemic lupus erythematosus (SLE)
-tobacco smoker
-vaginal bleeding
-an unusual or allergic reaction to estrogens, progestins, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using BIJUVA?

Visit your health care provider for regular checks on your progress. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your health care provider and follow their guidelines.
Tobacco smoking increases the risk of getting a blood clot or having a heart attack or stroke. Avoid smoking.
If you are going to need surgery or other procedure, tell your health care provider that you are using this medicine.

Where should I keep my medicine?

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:

-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, empty the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.