Clotrimazole Risks, Warnings, and Complications

Precautions Before Starting Clotrimazole

Tell your doctor if you have had allergic reactions to clotrimazole or any other medicines in the past. Also, tell your doctor about any pre-existing medical conditions. Give your doctor and pharmacist a complete list of medications, including prescription drugs, over-the-counter medicines, vitamins, supplements, and herbal products. This can help avoid possible drug interactions. Tell your doctor if you are pregnant, could be pregnant, are planning a pregnancy, or are breastfeeding.

Precautions During Use of Clotrimazole

If your fungal infection does not clear after clotrimazole treatment for 2 weeks for jock itch or 4 weeks for athlete’s foot and ringworm, tell your doctor. Pregnant women should talk to a healthcare professional before applying clotrimazole. This medicine should not be used in children under the age of 2 years unless a doctor tells you to.

Clotrimazole Drug Interactions

Using clotrimazole with certain other drugs can affect how it works. Possible drug interactions between clotrimazole and other medicines can also increase the risk of severe adverse effects. The following medications can have possible drug interactions with clotrimazole: 

• Tacrolimus
• Trimetrexate

The above list may not describe all possible interactions of clotrimazole. Give your doctor or pharmacist a complete list of your medications, including prescription drugs, over-the-counter medications, dietary supplements, and herbal remedies. Also, tell your health care professional if you smoke, drink alcohol, or use recreational drugs because some of these substances can cause serious health complications when used with medications.