Warnings


What may interact with Afrezza?


-albuterol or other inhaled medicines
-other medicines for diabetes

Many medications may cause changes in blood sugar, these include:

-alcohol containing beverages
-antiviral medicines for HIV or AIDS
-aspirin and aspirin-like medicines
-certain medicines for blood pressure, heart disease, irregular heart beat
-certain medicines for depression, anxiety, or psychotic disturbances
-chromium
-diuretics
-female hormones, like estrogens or progestins and birth control pills
-fenofibrate
-gemfibrozil
-isoniazid
-lanreotide
-male hormones or anabolic steroids
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
-medicines for weight loss
-medicines for allergies, asthma, cold, or cough
-niacin
-nicotine
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-octreotide
-pasireotide
-pentamidine
-phenytoin
-probenecid
-quinolone antibiotics such as ciprofloxacin, levofloxacin, ofloxacin
-some herbal dietary supplements
-steroid medicines like prednisone or cortisone
-sulfamethoxazole; trimethoprim
-thyroid hormones

Some medications can hide the warning symptoms of low blood sugar (hypoglycemia). You may need to monitor your blood sugar more closely if you are taking one of these medications. These include:

-beta-blockers like metoprolol and propranolol
-clonidine
-guanethidine
-reserpine

What should I tell my health care provider before I take Afrezza?

They need to know if you have any of these conditions:

-cigarette smoker
-episodes of low blood sugar
-kidney disease
-liver disease
-lung cancer
-lung or breathing disease, like asthma or COPD (such as emphysema)
-using other inhaled medicines
-an unusual or allergic reaction to insulin, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using Afrezza?

Visit your health care professional or doctor for regular checks on your progress.

A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.

Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.

Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.

Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.

Where should I keep my medicine?

Keep out of the reach of children.

The inhaler device can be used for up to 15 days from the date of first use. Throw away your inhaler after 15 days and get a new one. Between uses, store the inhaler between 2 and 25 degrees C (36 and 77 degrees F).
Store unopened foil cartridge packages in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). These may be used until the expiration date. If unopened insulin cartridges in foil packages are not refrigerated, the cartridges must be used within 10 days.
Opened foil insulin cartridge packages that are in use should be stored at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Sealed (unopened) blister cards and strips must be used within 10 days. Cartridges left over in an opened strip must be used within 3 days.
Before use, the inhaler and the cartridges should be at room temperature for 10 minutes.