Do not take this medicine with any of the following medications:

-cidofovir
-eplerenone
-tranylcypromine
This medicine may also interact with the following medications:

-aspirin
-certain medicines for blood pressure, heart disease like benazepril, lisinopril, losartan, valsartan
-certain medicines that treat or prevent blood clots like heparin and enoxaparin
-cholestyramine
-cyclosporine
-digoxin
-lithium
-medicines that relax muscles for surgery
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-other diuretics
-potassium supplements
-steroid medicines like prednisone or cortisone
-trimethoprim

They need to know if you have any of these conditions:

-diabetes
-immune system problems, like lupus
-kidney disease
-liver disease
-an unusual reaction to spironolactone, hydrochlorothiazide, sulfa drugs, other medicines, foods, dyes, or preservatives
-breast-feeding
-pregnant or trying to get pregnant

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor what your blood pressure should be, and when you should contact them.
This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.
You must not get dehydrated. Ask your doctor or health care professional how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Talk to your health care professional about your risk of skin cancer. You may be more at risk for skin cancer if you take this medicine.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused drug after the expiration date.