Warnings


What may interact with Aptivus?

Do not take this medicine with any of the following medications:

-boceprevir
-cisapride
-lurasidone
-medicines for cholesterol like lovastatin, simvastatin
-medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
-medicines for irregular heart beat like amiodarone, bepridil, flecainide, propafenone, quinidine
-midazolam
-naloxegol
-pimozide
-ranolazine
-red yeast rice
-rifampin
-rifapentine
-St. John''s wort
-triazolam



This medicine may also interact with the following medications:

-clarithromycin
-colchicine
-cyclosporine
-disulfiram
-dofetilide
-female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
-medicines for blood pressure like diltiazem, felodipine, verapamil
-medicines for cholesterol like atorvastatin
-medicines for depression, anxiety, or psychotic disturbances
-medicines for diabetes
-medicines for erectile dysfunction
-medicines for fungal infections like fluconazole, ketoconazole, itraconazole, voriconazole
-meperidine
-methadone
-metronidazole
-other medicines for HIV
-rifabutin
-sirolimus
-tacrolimus
-warfarin

What should I tell my health care provider before I take Aptivus?

They need to know if you have any of these conditions:

-diabetes
-hemophilia
-if you are taking any female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
-liver disease
-an unusual or allergic reaction to tipranavir, sulfa medicines, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using Aptivus?

Visit your doctor or health care provider for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.

HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.

This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.

Some products may contain alcohol. Ask your pharmacist or healthcare provider if this medicine contains alcohol. Be sure to tell all healthcare providers you are taking this medicine. Certain medicines, like metronidazole and disulfiram, can cause an unpleasant reaction when taken with alcohol. The reaction includes flushing, headache, nausea, vomiting, sweating, and increased thirst. The reaction can last from 30 minutes to several hours.

Where should I keep my medicine?

Keep out of the reach of children.

Before opening the bottle, store this medicine in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). After opening the bottle, store this medicine at room temperature between 20 and 25 degrees C (68 and 77 degrees F). This medicine must be used within 60 days of opening the bottle. Throw away any unused medicine after 60 days and after the expiration date.