Chlorthalidone

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 26, 2022

Common Questions


Common Questions about Chlorthalidone


Is chlorthalidone a water pill?

Yes, chlorthalidone is a water pill. Specifically, it is a thiazide-like diuretic



Do you need to take potassium with chlorthalidone?

If you have normal kidney function and are on a low dose of chlorthalidone, your doctor will likely advise you to get potassium from your diet. However, if you have low serum potassium levels or are at risk of developing low serum potassium, your doctor may prescribe potassium-sparing diuretics instead of chlorthalidone or recommend a potassium supplement.



What is the best time of day to take chlorthalidone?

It is best to take chlorthalidone in the morning with breakfast. Taking this medication in the evening can result in frequent awakenings during the night to urinate.



How long does it take for chlorthalidone to work?

Chlorthalidone starts working 2-3 hours after you take a tablet. However, it can take 1-2 weeks for you to notice an improvement in your high blood pressure.



Is chlorthalidone safe for kidneys?

Chlorthalidone works by helping the kidneys get rid of excess salt and water in the body. It can be hard on the kidneys, especially if you have pre-existing kidney problems. Your doctor might check kidney function before starting you on chlorthalidone and monitor it while you are on this medicine.



What is the price of chlorthalidone without insurance?

Without insurance, chlorthalidone can be as high as $35.99, but with a free BuzzRx prescription discount coupon, you could pay as low as $10.74 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of chlorthalidone with insurance? (brand or generic drug)

Ask your pharmacist or insurance provider for your copay price on chlorthalidone—copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins. 

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for chlorthalidone. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.