What may interact with CombiPatch?

Do not take this medicine with any of the following medications:
-aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone

This medicine may also interact with the following medications:
-barbiturates, such as phenobarbital
-grapefruit juice
-hydrocortisone, cortisone, or prednisolone
-isoniazid (INH)
-medications for diabetes
-mineral oil
-rifabutin, rifampin, or rifapentine
-thyroid hormones
-tricyclic antidepressants

What should I tell my health care provider before I take CombiPatch?

They need to know if you have any of these conditions:
-blood vessel disease or blood clots
-breast, cervical, endometrial, or uterine cancer
-gallbladder disease
-heart disease or recent heart attack
-high blood cholesterol
-high blood pressure
-high level of calcium in the blood
-kidney disease
-liver disease
-mental depression
-migraine headaches
-systemic lupus erythematosus (SLE)
-tobacco smoker
-vaginal bleeding
-an unusual or allergic reaction to estrogens, progestins, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant

What should I watch for while using CombiPatch?

Visit your health care professional for regular checks on your progress. You should have a complete check-up every 6 months. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines.

This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.

Tobacco smoking increases the risk of getting a blood clot or having a stroke, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.

If you are going to have elective surgery, you may need to stop taking this medicine beforehand. Consult your health care professional for advice prior to scheduling the surgery.

If you are going to have a MRI procedure, let your MRI technician know about the use of these patches. Some drug patches contain an aluminized backing that can become heated when exposed to MRI and may cause burns. You may need to temporarily remove the patch during the MRI procedure.

You may bathe or participate in other activities while wearing your patch. If your patch falls off reapply it. If you cannot reapply the patch, apply a new patch to another area and continue to follow your usual dose schedule.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) in the sealed foil pouch. Throw away any unused medicine after 6 months or the expiration date on the package, whichever is sooner.