Hydrochlorothiazide

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 13, 2022

Common Questions


Common Questions about Hydrochlorothiazide


What is the best time to take hydrochlorothiazide?

If you are on a single oral dose of hydrochlorothiazide, it is best to take it in the morning after breakfast. If you are on more than one dose a day, try to take the last dose before 6 pm unless otherwise advised by your doctor. This medication can make you pee a lot. Taking it later in the evening might cause you to get up in the night to urinate.



Can I drink coffee while taking hydrochlorothiazide?

It is best to avoid drinking coffee, especially excessive amounts of caffeine, while on hydrochlorothiazide. Caffeine can raise blood pressure. Also, taking caffeine with water pills like hydrochlorothiazide can lead to serum potassium depletion (too low serum potassium levels).



Does hydrochlorothiazide lead to weight loss?

Hydrochlorothiazide helps the body get rid of excess fluid. This can result in loss of water weight. However, this medication will not lead to fat loss.



What are the dangers of taking hydrochlorothiazide?

Hydrochlorothiazide is a relatively safe medication when it is taken as directed. Most people tolerate it well with few side effects. However, hydrochlorothiazide can lead to dehydration and electrolyte imbalance. Contact your doctor right away if you experience excessive thirst, dry mouth, drowsiness, tiredness, increased heart rate, muscle pain or cramps, nausea, or vomiting.



Who should not take hydrochlorothiazide?

Hydrochlorothiazide is contraindicated in people who have an allergy to this medicine and in people with anuria (inability to urinate).



What is the price of hydrochlorothiazide without insurance?

Without insurance, hydrochlorothiazide can be as high as $29.99, but with a free BuzzRx prescription discount coupon, you could pay as low as $4.04 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can use your BuzzRx card and coupons to purchase brand-name versions of hydrochlorothiazide like Microzide. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.



What is the price of hydrochlorothiazide with insurance?

Ask your pharmacist or insurance provider for your copay price on hydrochlorothiazide—copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for hydrochlorothiazide. When using the BuzzRx lookup tool to find the price of your medication, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.