Indomethacin Side Effects

Common side effects of indomethacin are listed below. Tell your doctor if these side effects are severe or if they do not go away in a few days. 

• Headache
• Dizziness
• Nausea, vomiting, diarrhea, constipation
• Ringing in the ears

Some of the adverse reactions of indomethacin can be more serious. Call your healthcare professional right away or seek emergency medical help if you experience the following signs and symptoms while on indomethacin:

• Shortness of breath or trouble breathing
• Chest pain
• Swelling of the face, throat, tongue, lips, or hands
• Swelling of the abdomen, legs, ankles, or feet
• Unexplained weight gain
• Unusual or allergic reaction 
• Serious skin reactions (rash, hives, blisters, itching)
• Fever or flu-like symptoms
• Lymph node swelling
• Pale skin
• Extreme fatigue, unusual tiredness, lack of energy
• Fast heartbeat
• Unusual bruising or bleeding
• Nausea, vomiting, right upper stomach pain, loss of appetite, yellowing of the skin or eyes
• Discolored, cloudy, or bloody urine
• Pain with urination
• Back pain
• Vision problems, such as blurred vision

The above list may not include all the potential side effects of indomethacin. Contact your healthcare provider if your side effects are unusual or severe or they do not get better over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Indomethacin Overdose: In case of an accidental or intentional overdose of indomethacin, call your doctor immediately or call the local poison control center or national poison control center at 1-800-222-1222. Signs and symptoms of  indomethacin overdose may include headache, dizziness, confusion, nausea, vomiting, extreme tiredness, numbness and tingling, and seizures.

Source: FDA