Pros & Cons


Irbesartan Hydrochlorothiazide (Avalide) Pros and Cons

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  • Irbesartan hydrochlorothiazide combines two effective antihypertensive drugs in one pill. The two drugs have additive antihypertensive effects and can be effective in controlling high blood pressure in people who have not responded to one antihypertensive drug.
  • You only need to take this combination medicine once daily.
  • Irbesartan hydrochlorothiazide can be taken with other medicines to control high blood pressure if needed.
  • There is a lower-cost generic available.

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  • Irbesartan and hydrochlorothiazide come in a fixed dose combination. It is therefore not possible to adjust the dose of each medicine individually.
  • You need regular blood tests to monitor kidney function and electrolyte levels while on irbesartan hydrochlorothiazide.
  • Common side effects include increased urination, dizziness, and headache.
  • It is only available in tablet form.
  • Irbesartan hydrochlorothiazide is not safe for use by pregnant women.