Do not take this medicine with any of the following medications:

-certain medicines for cholesterol like atorvastatin, lomitapide, lovastatin, simvastatin
-certain medicines for irregular heart beat like dronedarone, quinidine
-cisapride
-ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
-ibrutinib
-lapatinib
-naloxegol
-other medicines that prolong the QT interval (cause an abnormal heart rhythm)
-pimozide
-sirolimus
-thioridazine
This medicine may also interact with the following medications:

-antiviral medicines for HIV or AIDS
-certain medicines for anxiety or sleep like alprazolam, midazolam, triazolam
-certain medicines for blood pressure like diltiazem, nifedipine, nicardipine, verapamil
-certain medicines for cancer like vinblastine, vincristine
-certain medicines for diabetes like glipizide
-certain medicines for seizures like phenytoin
-digoxin
-dofetilide
-medicines that lower your chance of fighting infection like cyclosporine, tacrolimus
-metoclopramide
-other medicines for fungal infections
-rifabutin
-ziprasidone

They need to know if you have any of these conditions:

-heart disease
-history of irregular heartbeat
-history of low levels of calcium, magnesium, or potassium in the blood
-kidney disease
-liver disease
-an unusual or allergic reaction to posaconazole, antifungals, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse. You may need blood work while you are taking this medicine.
If you get severe diarrhea or vomiting tell your health care provider right away. You may not get your full dose of medicine if you are sick.

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:

-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, take the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.