Do not take this medication with any of the following:
-Aripiprazole
-Metoclopramide
This medication may also interact with the following:
-Antihistamines for allergy, cough, and cold
-Certain medications for anxiety or sleep
-Certain medications for depression, such as amitriptyline, duloxetine, fluoxetine, paroxetine, sertraline
-Certain medications for fungal infections, such as fluconazole, itraconazole, ketoconazole
-Certain medications for Parkinson disease, such as levodopa
-Clarithromycin
-General anesthetics, such as halothane, isoflurane, methoxyflurane, propofol
-Medications for blood pressure
-Medications that relax muscles for surgery
-Medications for seizures
-Opioid medications for pain
-Phenothiazines, such as chlorpromazine, prochlorperazine, thioridazine
-Quinidine
-Rifampin
-St. John's wort

They need to know if you have any of these conditions:
-Dementia
-Diabetes
-Have trouble controlling your muscles
-Heart disease
-High cholesterol
-History of breast cancer
-History of stroke
-Kidney disease
-Liver disease
-Low blood cell levels (white cells, red cells, and platelets)
-Low blood pressure
-Parkinson disease
-Seizures
-Suicidal thoughts, plans, or attempt by you or a family member
-Trouble swallowing
-Urges to engage in impulsive behaviors in ways that are unusual for you
-An unusual or allergic reaction to brexpiprazole, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breastfeeding

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
Do not suddenly stop taking this medication. You may develop a severe reaction. Your care team will tell you how much medication to take. If your care team wants you to stop the medication, the dose may be slowly lowered over time to avoid any side effects.
This medication may cause thoughts of suicide or depression. This includes sudden changes in mood, behaviors, or thoughts. These changes can happen at any time but are more common in the beginning of treatment or after a change in dose. Call your care team right away if you experience these thoughts or worsening depression.
This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
There have been reports of increased sexual urges or other strong urges, such as gambling while taking this medication. If you experience any of these while taking this medication, you should report this to your care team as soon as possible.
This medication may cause dry eyes and blurred vision. If you wear contact lenses, you may feel some discomfort. Lubricating eye drops may help. See your care team if the problem does not go away or is severe.
This medication may increase blood sugar. Ask your care team if changes in diet or medications are needed if you have diabetes.
This medication can cause problems with controlling your body temperature. It can lower the response of your body to cold temperatures. If possible, stay indoors during cold weather. If you must go outdoors, wear warm clothes. It can also lower the response of your body to heat. Do not overheat. Do not over-exercise. Stay out of the sun when possible. If you must be in the sun, wear cool clothing. Drink plenty of water. If you have trouble controlling your body temperature, call your care team right away.

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.