Oral capsule|Oral tablet
SELEGILINE (se LE ji leen) is an monoamine oxidase inhibitor (MAOI). It is used with levodopa-carbidopa in the treatment of Parkinson''s disease. It is usually added to therapy when there is a decrease in response to levodopa.
Selegiline may be used for other purposes; ask your health care provider or pharmacist if you have questions
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of Selegiline contact a poison control center or emergency room at once. NOTE: Selegiline is only for you. Do not share Selegiline with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-changes in emotions or moods
-falling asleep during normal activities like driving
-high blood pressure
-new or increased gambling urges, sexual urges, uncontrollable spending, binge or compulsive eating, or other urges
-signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
-signs and symptoms of hypertensive crisis like severe sudden headache; excess sweating, sometimes with a fever or cold and clammy skin; eyes sensitive to light; fast, irregular heartbeat
-uncontrollable movements of the arms, face, head, mouth, neck, and upper body
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
This list may not describe all possible side effects for Selegiline. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.Source: FDA
Do not take this medicine with any of the following medications:
-MAOIs like Marplan, Nardil, and Parnate
-other medicines containing selegiline, like Emsam or Eldepryl
-stimulant medicines for attention disorders
-St. John''s wort
This medicine may also interact with the following medications:
-certain medicines for depression, anxiety, or psychotic disorders
-epinephrine or racepinephrine
-medicines for nasal congestion like phenylephrine, pseudoephedrine
-narcotic medicines for pain
-stimulant medicines for weight loss or staying awake
They need to know if you have any of these conditions:
-high blood pressure
-low blood pressure
-an unusual or allergic reaction to selegiline, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
Visit your health care professional for regular checks on your progress. Tell your health care professional if your symptoms do not start to get better or if they get worse. Do not stop taking except on your health care professional''s advice. You may develop a severe reaction. Your health care professional will tell you how much medicine to take.
This medicine can interact with certain foods that contain high amounts of tyramine. The combination may cause severe headaches, a rise in blood pressure, or irregular heart beat. Foods that contain significant amounts of tyramine include aged cheeses, meats and fish (especially aged, smoked, pickled, or processed such as bologna, pepperoni, salami, summer sausage), beer and ale, alcohol-free beer, wine (especially red), sherry, hard liquor, liqueurs, avocados, bananas, figs, raisins, soy sauce, miso soup, yeast/protein extracts, bean curd, fava or broad bean pods, or any over-ripe fruit. Ask your doctor or health care professional, pharmacist, or nutritionist for a complete listing of tyramine-containing foods.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your health care professional if the problem does not go away or is severe.
Do not treat yourself for coughs, colds, flu or allergies without asking your doctor or health care professional for advice. Do not take any medications for weight loss without advice either. Some ingredients in these products may increase possible side effects.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
If you are scheduled for any medical or dental procedure, tell your healthcare provider that you are taking this medicine. This medicine can interact with other medicines used during surgery.
You should check your skin often for changes to moles and new growths while taking this medicine. Call your doctor if you notice any of these changes.
Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:
-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, take the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.