Trintellix

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 20, 2022

Common Questions


Common Questions about Trintellix


Is Trintellix good for anxiety?

The U.S. Food and Drug Administration (FDA) has only approved Trintellix to treat major depressive disorder. However, it may be used off-label to treat anxiety.



What makes Trintellix different?

Trintellix is different from other antidepressants because it directly affects serotonin receptors in the brain. Also, Trintellix is less likely to cause weight gain and sexual dysfunction compared to other antidepressants, including tricyclic antidepressants, monoamine oxidase inhibitors, and selective serotonin reuptake inhibitors (SSRIs).



How long does it take for Trintellix to work?

It can take 2-4 weeks to get the full benefits of Trintellix treatment. Talk to your doctor if you don’t notice any improvement in your depression symptoms after 6-8 weeks. Your doctor may increase your dose or change you to another antidepressant medication.



Is Trintellix better than Zoloft?

Placebo-controlled trials have shown that people on antidepressants obtain more relief from depressive symptoms compared to placebo-treated patients. Both Trintellix and Zoloft are effective antidepressants. Your doctor can help you choose the right one for you.



Is Trintellix different from Prozac?

Prozac belongs to a group of antidepressants called selective serotonin reuptake inhibitors (SSRIs). Trintellix is not in any specific class of antidepressants, called an atypical antidepressant. Both Prozac and Trintellix work similarly by increasing serotonin levels. However, they are not the same. Your doctor can help you decide which medicine is right for you.



What is the price of Trintellix without insurance?

Without insurance, Trintellix can be as high as $558.99, but with a free BuzzRx prescription discount coupon, you could pay as low as $444.37 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.



What is the price of Trintellix with insurance?

Ask your pharmacist or insurance provider for your copay price on Trintellix—copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for Trintellix. When using the BuzzRx lookup tool to find the price of your medication, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.