Warnings


What may interact with Xiaflex?

-Aspirin and aspirin-like medications
-Certain medications that treat or prevent blood clots, such as warfarin, enoxaparin, dalteparin, apixaban, dabigatran, rivaroxaban

What should I tell my health care provider before I take Xiaflex

They need to know if you have any of these conditions:
-Bleeding disorder
-An unusual or allergic reaction to collagenase, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breast-feeding

What should I watch for while using Xiaflex?

Your condition will be monitored carefully while you are receiving this medication.
If medication is for Dupuytren's Contracture, visit your care team 1 to 3 days after the injection. Until you visit your care team, do not flex or extend the fingers of your hand that was injected. Do not touch your finger that was injected. Elevate your hand until bedtime. Do not perform activity with the injected hand until you are told that it is ok. Follow any instructions about wearing a splint or performing finger exercises. Contact your care team as soon as possible if you get increasing redness or swelling in the hand, have numbness or tingling in the treated finger, or have trouble bending the finger after the swelling goes down.
If medication is for Peyronie's disease, do not have sex between the first and second injections. Wait 4 weeks after the second injection and when there is no more pain or swelling in the penis to have sex. Avoid using vacuum erection devices during treatment with this medication. Try to avoid straining stomach muscles such as during bowel movements. Your care team will give you instructions on how to perform modeling activities at home. Contact your care team as soon as possible if you have severe pain or swelling in the penis, severe purple bruising and swelling of the penis, trouble passing urine, blood in urine, popping or cracking sound form the penis, or sudden loss of ability to maintain an erection.

Where should I keep my medicine?

This medication is given in a hospital or clinic. It will not be stored at home.