Do not take this medicine with any of the following medications:
-alcohol or medicines that contain alcohol
-cidofovir
-furazolidone
-methotrexate
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
-probenecid
-procarbazine
-voriconazole
-warfarin

This medicine may also interact with the following medications:
-antidepressants
-antihistamines
-benzodiazepines
-heparin and heparin like drugs including enoxaparin, dalteparin, and tinzaparin
-medicines for pain
-muscle relaxants
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

They need to know if you have any of these conditions:

-drink more than 3 alcohol containing drinks per day
-drug abuse or addiction
-heart or circulation problems
-hemophilia, von Willebrand''s disease, low platelets, or other bleeding problems
-kidney disease or problems going to the bathroom
-liver disease
-lung disease like asthma or emphysema
-peptic ulcer disease
-porphyria
-an unusual or allergic reaction to aspirin or salicylates, butalbital or other barbiturates, caffeine, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Tell your doctor or health care provider if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take the medicine for a long time.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
You may get drowsy or dizzy when you first start taking the medicine or change doses. Do not drive, use machinery, or do anything that may be dangerous until you know how the medicine affects you. Stand or sit up slowly.
Do not take other medicines that contain aspirin, ibuprofen, or naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many non-prescription medicines contain aspirin, ibuprofen, or naproxen. Always read labels carefully.
This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
Talk to your health care provider if you are pregnant before taking this medicine. Taking this medicine between weeks 20 and 30 of pregnancy may harm your unborn baby. Your health care provider will monitor you closely if you need to take it. After 30 weeks of pregnancy, do not take this medicine.
This medicine can cause serious ulcers and bleeding in the stomach. It can happen with no warning. Smoking, drinking alcohol, older age, and poor health can also increase risks. Call your health care provider right away if you have stomach pain or blood in your vomit or stool.
This medicine does not prevent a heart attack or stroke. This medicine may increase the chance of a heart attack or stroke. The chance may increase the longer you use this medicine or if you have heart disease. If you take aspirin to prevent a heart attack or stroke, talk to your health care provider about using this medicine.
Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Keep out of the reach of children and pets.
This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
This medicine may cause accidental overdose and death if it is taken by other adults, children, or pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).
Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:

-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, empty the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.