Medically Reviewed by Dr. Harshi Dhingra, M.D.
Last Reviewed: Jul 20, 2022
Januvia can cause serious health problems, especially in certain high-risk patients. Some of the risks of Januvia therapy include:
Tell your healthcare provider if you have ever had an allergic reaction to Januvia, any of the ingredients in Januvia tablets, or any other medications. Your pharmacy can give you a list of ingredients.
Give your healthcare provider a complete medical history. Januvia may not be suitable for people with certain medical conditions such as pancreatitis, heart failure, kidney disease, gallstones, or high triglycerides. Also, tell your doctor if you have ever had diabetic ketoacidosis and if you drink or have ever drunk large amounts of alcohol.
Give your doctor a complete list of all your medications, including prescription drugs, over-the-counter medicines, vitamins, dietary supplements, and herbal products. This can help avoid serious interactions between Januvia and other drugs.
Tell your doctor if you are pregnant, could be pregnant, plan to get pregnant, or are breastfeeding.
Talk with your doctor about the symptoms of high and low blood sugar and what to do should they occur.
Keep all your medical and lab appointments while on Januvia. Your doctor may want to check how well the medication is working to improve glycemic control (blood sugar levels). Your provider may order certain laboratory tests to monitor your kidney function during treatment with this medication.
Tell your doctor if there are any significant changes in your diet, exercise levels, or weight; if you become dehydrated or if you are eating or drinking less due to an illness that causes nausea, vomiting, and diarrhea; or if you are undergoing surgery, have an infection and/or fever, are experiencing unusual stress, or have suffered an injury. These conditions can lead to fluctuations in blood sugar levels and may affect the amount of Januvia you need.
Tell your health care professionals you are on Januvia before undergoing any surgery, including dental surgery.
Call your doctor if you become pregnant while on Januvia.
Taking Januvia together with some other medications can affect how the medications work. Interactions between medications can also increase the risk of serious adverse reactions. Your physician may choose different diabetes medications for you, change the dose or frequency of one or both medicines, and/or closely monitor you for side effects if there are known interactions between Januvia and your other medications.
There can be potential interactions between Januvia and the following medications:
This list does not describe all possible Januvia interactions. Give your healthcare professionals a complete list of your medications, including prescription drugs, over-the-counter medicines, vitamins, dietary supplements, and herbal products. Also, tell your health care provider if you smoke, drink alcohol, or use illegal drugs because some of these substances can cause serious health complications when used with prescription drugs.