Side Effects


What side effects may I notice from receiving Diflunisal?

Side effects that you should report to your doctor or health care provider as soon as possible:

-allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
-blood clot (chest pain; shortness of breath; pain, swelling, or warmth in the leg)
-heart attack (trouble breathing; pain or tightness in the chest, neck, back or arms; unusually weak or tired)
-heart failure (trouble breathing; fast, irregular heartbeat; sudden weight gain; swelling of the ankles, feet, hands; unusually weak or tired)
-increase in blood pressure
-kidney injury (trouble passing urine or change in the amount of urine)
-liver injury (dark yellow or brown urine; general ill feeling or flu-like symptoms; loss of appetite, right upper belly pain; unusually weak or tired, yellowing of the eyes or skin)
-low red blood cell counts (trouble breathing; feeling faint; lightheaded, falls; unusually weak or tired)
-rash, fever, and swollen lymph nodes
-redness, blistering, peeling, or loosening of the skin, including inside the mouth
-stomach bleeding (bloody or black, tarry stools; spitting up blood or brown material that looks like coffee grounds)
-stroke (changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm or leg; trouble walking; dizziness; loss of balance or coordination)
Side effects that usually do not require medical attention (report to your doctor or health care provider if they continue or are bothersome):

-diarrhea
-eye irritation, itching
-headache
-nausea
-upset stomach
-stomach pain

This list may not describe all possible side effects for Diflunisal. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA