Glipizide

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Oct 30, 2023

Common Questions


Common Questions about Glipizide


Is metformin and glipizide the same thing?

No, metformin and glipizide are not the same thing. Both are oral medications used to treat type 2 diabetes. However, glipizide belongs to a group of drugs called sulfonylureas that work by stimulating insulin production in the pancreas. Metformin belongs to a group of drugs called biguanide that decrease glucose formation in the liver and increase insulin sensitivity.



Is glipizide stronger than glimepiride?

Glipizide (brand name Glucotrol) and glimepiride (brand name Amaryl) are both sulfonylureas. Both medications are effective in lowering blood sugar levels. However, studies have shown that glimepiride may provide more effective blood sugar control in the first few weeks of treatment.



Can you take glipizide and metformin together?

Yes, you can take glipizide and metformin together if your doctor prescribes them. The combination is not only safe but also very effective in controlling blood sugar levels in people with type 2 diabetes mellitus.



What is the best time to take glipizide for diabetes?

The best time to take glipizide for diabetes is 30 minutes before breakfast if you are on a once-daily dosing of the immediate-release tablets. You should take the medicine 30 minutes before breakfast and other main meals of the day if you are taking this medicine in divided doses. The extended release glipizide oral tablet should be taken with breakfast once daily.



How quickly does glipizide start working?

Glipizide immediate-release tablets start working within 30 minutes of taking a dose and have a peak effect in 1-3 hours. The extended-release tablets reach their full effects in 6-12 hours and can lower blood sugar for 12-24 hours.



What is the price of glipizide without insurance?

Without insurance, glipizide can be as high as $77.99, but with a free BuzzRx prescription discount coupon, you could pay as low as $16.24 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of glipizide with insurance?

Ask your pharmacist or insurance provider for your copay price on glipizide—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for glipizide. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.