Do not take this medicine with any of the following medications:

-alfuzosin
-atazanavir
-certain medicines for cholesterol like lovastatin, red yeast rice, simvastatin
-chloroquine
-cisapride
-clarithromycin
-clozapine
-cobicistat
-dasatinib
-droperidol
-erythromycin
-garlic supplements
-haloperidol
-lurasidone
-medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
-medicines for irregular heart beat like amiodarone, bepridil, disopyramide, flecainide, ibutilide, lidocaine, propafenone, quinidine
-methadone
-midazolam
-naloxegol
-pentamidine
-phenothiazines like chlorpromazine, fluphenazine, perphenazine, prochlorperazine, thioridazine, trifluoperazine
-pimozide
-quinine
-ranolazine
-rifampin
-rilpivirine
-sertindole
-sildenafil
-St. John''s wort
-sunitinib
-tacrolimus
-trazodone
-triazolam
This medicine may also interact with the following medications:

-alfentanil
-atorvastatin
-arsenic trioxide
-bosentan
-certain medicines for blood pressure, heart disease, irregular heart beat like amlodipine, digoxin, diltiazem, felodipine, ibutilide, isradipine, nifedipine, nicardipine, nimodipine, nisoldipine, procainamide, sotalol, verapamil
-colchicine
-cyclosporine
-corticosteroids like betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, prednisone, triamcinolone
-dofetilide
-female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
-fentanyl
-medicines for depression, anxiety, or psychotic disturbances like alprazolam, amitriptyline, clomipramine, clorazepate, diazepam, flurazepam, imipramine, maprotiline, nefazodone, quetiapine
-medicines for diabetes
-medicines for erectile dysfunction like tadalafil and vardenafil
-medicines for infections like dapsone, fusidic acid, ketoconazole, itraconazole, quinupristin; dalfopristin, rifabutin, rifapentine
-medicines for seizures like carbamazepine, phenobarbital, phenytoin
-medicines for stomach problems like esomeprazole, omeprazole, pantoprazole, rabeprazole, ranitidine
-other medicines for HIV like delavirdine, efavirenz, maraviroc, nelfinavir, nevirapine, indinavir, lopinavir; ritonavir, tipranavir
-sirolimus
-vincamine
-warfarin
-ziprasidone

They need to know if you have any of these conditions:

-diabetes
-heart disease
-hemophilia
-history of irregular heartbeat
-history of low levels of calcium, magnesium, or potassium in the blood
-liver disease
-an unusual or allergic reaction to saquinavir, lactose, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care providerfor regular check-ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.

Keep out of the reach of children.
Store tightly closed at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.