-any stimulant drug
-beta-blockers or calcium-channel blockers, often used for high blood pressure, angina, or other heart problems
-medicines for high blood pressure
-medicines for colds, sinus problems, or breathing problems
-medicines for diabetes
-medicines for depression, anxiety, or psychotic disturbances
-medicines for irregular heart beat like amiodarone or digoxin
-reserpine
Do not use any other eye products without telling your doctor or health care professional.

They need to know if you have any of these conditions:

-diabetes
-eye abrasion, infection, or inflammation
-heart disease, heart rhythm problems, or blood vessel disease (Raynaud''s disease)
-lung or breathing disease, like asthma
-muscle weakness or muscle disease (such as myasthenia gravis)
-pheochromocytoma
-thyroid disease
-wear contact lenses
-any usual or allergic reaction to metipranolol or other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care professional for regular checks on your progress. Report any serious side effects right away. Stop using this medicine if your eyes get swollen, painful, or have a discharge, and see your doctor or health care professional as soon as you can.

Ask your doctor or health care professional if you should keep using this medicine if your eye condition changes (examples: injure your eye, get an eye infection, or need eye surgery).

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that requires mental alertness until you know how this medicine affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly.

If you wear contact lenses, remove them before putting drops in the eye. You may put your contact lenses back in 15 minutes after putting the drops in your eye.

Be careful not to touch the tip of the dispensing container onto the eye, or any other surface. Serious eye infections can result from contamination of eye solutions.

If you are using another eye-care product , there should be an interval of at least 5 minutes between use of this medicine and the other eye-care product.

Wear dark glasses if this medicine makes your eyes more sensitive to light.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Replace cap immediately after use. Throw away any unused medicine after the expiration date.