Oxycodone-Acetaminophen

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Sep 25, 2023

Pros & Cons


Oxycodone-Acetaminophen Pros and Cons

pros header.svg

  • The combination of oxycodone and acetaminophen provides fast relief from moderate to severe pain within 30 minutes of taking a dose.
  • It is available in a lower-cost generic form.
  • You can take it as needed to manage pain. 
  • It is a combination of two medications in one pill for convenience.
  • A liquid form of this opioid pain medicine is available for people who have trouble swallowing pills.

cons header.svg

  • You need to take oxycodone and acetaminophen every 6 hours for effective pain control.
  • Pain relievers such as oxycodone and acetaminophen, which contain an opioid medicine, are habit-forming and carry a high risk of abuse and opioid addiction.
  • Serious adverse reactions include life-threatening respiratory depression, which can be fatal.
  • Stopping this medication suddenly can cause withdrawal symptoms.
  • It is a controlled substance, and you need to meet special requirements before you will be given a prescription.