Do not take this medicine with any of the following medications:
-aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone
-metyrapone

This medicine may also interact with the following medications:
-barbiturates, such as phenobarbital
-carbamazepine
-clarithromycin
-erythromycin
-grapefruit juice
-medicines for fungal infections like ketoconazole and itraconazole
-phenytoin
- rifampin
-ritonavir
-St. John''s Wort
-thyroid hormones

They need to know if you have any of these conditions:
-abnormal vaginal bleeding
-blood vessel disease or blood clots
-breast, cervical, endometrial, ovarian, liver, or uterine cancer
-dementia
-diabetes
-endometriosis
-fibroids
-gallbladder disease
-heart disease or recent heart attack
-high blood pressure
-high cholesterol
-high level of calcium in the blood
-kidney disease
-liver disease
-mental depression
-migraine headaches
-protein C deficiency
-protein S deficiency
-stroke
-tobacco smoker
-an unusual or allergic reaction to estrogens, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your health care professional for regular checks on your progress. You will need a regular breast and pelvic exam and Pap smear while on this medicine. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines for these tests.

This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.

Smoking increases the risk of getting a blood clot or having a stroke while you are taking this medicine, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.

The tablet shell for some brands of this medicine does not dissolve. The tablet shell may appear whole in the stool. This is not a cause for concern. If you see something that resembles a tablet in your stool, talk to your healthcare provider.

This medicine can increase the risk of developing a condition (endometrial hyperplasia) that may lead to cancer of the lining of the uterus. Taking progestins, another hormone drug, with this medicine lowers the risk of developing this condition. Therefore, if your uterus has not been removed (by a hysterectomy), your doctor may prescribe a progestin for you to take together with your estrogen. You should know, however, that taking estrogens with progestins may have additional health risks. You should discuss the use of estrogens and progestins with your health care professional to determine the benefits and risks for you.

If you are going to have surgery, you may need to stop taking this medicine. Consult your health care professional for advice before you schedule the surgery.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.