Medically Reviewed by HaVy Ngo, Pharm.D.

Last Reviewed: Jun 15, 2022

Pros & Cons


What are the pros and cons of Pristiq?

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  • Available as a generic at a lower price
  • Once-a-day dosing is convenient and suitable for compliance.
  • Generally well-tolerated and effective at treating symptoms of depression and lowering the likelihood of recurrent depression
  • Can be taken with or without food

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  • Increased risks of suicidal thoughts and ideation in young adults who are 24 years or younger
  • It can take up from 6 to 8 weeks to see the full effects of this medication
  • Can raise blood pressure
  • Can increase risk of bleeding if being taken with NSAIDs or blood thinner
  • Can cause unpleasant withdrawal symptoms with sudden discontinuation
  • Not the safest choice for people with uncontrolled high blood pressure and heart disease