Warnings


What may interact with Sulfamethoxazole, Trimethoprim?

Do not take this medicine with any of the following medications:

-dofetilide
This medicine may also interact with the following medications:

-amantadine
-birth control pills
-certain medicines for blood pressure, heart disease
-certain medicines for depression, like amitriptyline
-certain medicines for diabetes, like glipizide or glyburide
-certain medicines that treat or prevent blood clots like warfarin
-cyclosporine
-digoxin
-diuretics
-indomethacin
-methotrexate
-phenytoin
-procainamide
-pyrimethamine
-zidovudine

What should I tell my health care provider before I take Sulfamethoxazole, Trimethoprim?

They need to know if you have any of these conditions:

-G6PD deficiency
-HIV or AIDS
-kidney disease
-liver disease
-low platelets
-low red blood cell counts
-poor nutrition
-stomach or intestine problems like colitis
-thyroid disease
-an unusual or allergic reaction to sulfamethoxazole, trimethoprim, sulfa drugs, other drugs, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using Sulfamethoxazole, Trimethoprim?

Tell your health care provider if your symptoms do not start to get better or if they get worse.
Do not treat diarrhea with over the counter products. Contact your health care provider if you have diarrhea that lasts more than 2 days or if it is severe and watery.
This drug may cause serious skin reactions. They can happen weeks to months after starting the drug. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.
This drug can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and sunscreen. Do not use sun lamps or tanning beds/booths.
Be careful brushing or flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this drug.

Where should I keep my medicine?

Keep out of the reach of children.
Store between 15 and 25 degrees C (59 to 77 degrees F). Protect from light. Keep the container tightly closed. Throw away any unused drug after the expiration date.