Warnings


What may interact with SymlinPen?


-acetaminophen
-alosetron
-atropine
-birth control pills
-certain medicines for bladder problems like oxybutynin
-certain medicines for stomach problems like dicyclomine, hyoscyamine
-certain medicines for travel sickness like scopolamine
-eluxadoline
-other medicines for diabetes like acarbose, miglitol

Many medications may cause changes in blood sugar, these include:

-alcohol containing beverages
-antiviral medicines for HIV or AIDS
-aspirin and aspirin-like drugs
-certain medicines for blood pressure, heart disease, irregular heart beat
-chromium
-diuretics
-female hormones, such as estrogens or progestins, birth control pills
-fenofibrate
-gemfibrozil
-isoniazid
-lanreotide
-male hormones or anabolic steroids
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
-medicines for weight loss
-medicines for allergies, asthma, cold, or cough
-medicines for depression, anxiety, or psychotic disturbances
-niacin
-nicotine
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-octreotide
-pasireotide
-pentamidine
-phenytoin
-probenecid
-quinolone antibiotics such as ciprofloxacin, levofloxacin, ofloxacin
-some herbal dietary supplements
-steroid medicines such as prednisone or cortisone
-sulfamethoxazole; trimethoprim
-thyroid hormones

Some medications can hide the warning symptoms of low blood sugar (hypoglycemia). You may need to monitor your blood sugar more closely if you are taking one of these medications. These include:

-beta-blockers, often used for high blood pressure or heart problems (examples include atenolol, metoprolol, propranolol)
-clonidine
-guanethidine
-reserpine

What should I tell my health care provider before I take SymlinPen?

They need to know if you have any of these conditions:

-hemoglobin A1C value above 9
-low blood sugar episodes
-problems checking blood sugar
-problems taking diabetes medicine
-stomach problems like gastroparesis
-trouble being able to tell when blood sugar is low
-an unusual or allergic reaction to pramlintide, metacresol, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using SymlinPen?

Visit your doctor or health care professional for regular checks on your progress.

A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.

Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.

Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.

Pens should never be shared. Even if the needle is changed, sharing may result in passing of viruses like hepatitis or HIV.

Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.

Where should I keep my medicine?

Keep out of the reach of children.

Store unopened injector-pens in the refrigerator between 2 to 8 degrees C (36 to 46 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.

Store opened injector-pens (pens currently in use) in the refrigerator or at room temperature of not greater than 30 degrees C (86 degrees F) for up to 30 days. Do not freeze. Keeping this medicine at room temperature decreases the amount of pain during injection. Throw away any opened pens of this medicine 30 days after opening.