Dexmethylphenidate ER

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Dec 11, 2023

Pharmacist Tips


Dexmethylphenidate Tips from Pharmacists

  • You can take dexmethylphenidate with or without food. If you have gastrointestinal side effects like an upset stomach, taking it with food might help. The extended-release capsule works slower if you take it with food.

  • Try to take your first dose of dexmethylphenidate in the morning and the second dose of the immediate-release formulation in the afternoon (at least 4 hours after your first dose). Avoid taking the medicine later in the evening as it can cause trouble sleeping at night.

  • Swallow the extended-release capsules whole without chewing, cutting, or crushing them. If you have trouble swallowing pills, you can sprinkle the contents of the capsule on a small amount of applesauce. Ensure that you swallow the mixture immediately without chewing. Do not pre-mix the medicine with applesauce for later use.

  • Do not stop taking dexmethylphenidate suddenly after taking it for a long time. This can cause withdrawal symptoms. Your provider will tell you how to lower the dose slowly or switch to another ADHD medicine.

  • Dexmethylphenidate can cause dizziness, drowsiness, and blurry vision. Avoid driving and other hazardous activities until you know how it affects you.