Doxylamine-Pyridoxine (Vit B6)

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: May 05, 2025

Doxylamine-Pyridoxine (Vit B6) Pharmacist Tips (Generic)


Doxylamine-Pyridoxine (Diclegis) Tips from Pharmacists

  • Take doxylamine-pyridoxine on an empty stomach with a full glass of water.

  • Do not cut, crush, or chew the tablets. The extended-release and delayed-release tablets are designed to release the medicine slowly over time in your body or in a delayed manner in the intestines.

  • Read the labels of other over-the-counter medications carefully. Do not take other products with the same active ingredients (doxylamine and pyridoxine), as this can increase your risk of severe side effects and overdose.

  • Other ways to manage morning sickness include eating dry crackers before getting out of bed in the morning, staying well hydrated, and eating smaller, more frequent meals throughout the day.