Estradiol

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 06, 2022

Common Questions


Common Questions about estradiol


Is weight gain a side effect of estradiol?

Weight gain can be a side effect of estradiol. However, it is worth noting that women tend to gain weight around their midsection after menopause, so the extra weight may not be from the medication. If you are concerned about weight gain, your doctor can provide medical advice about alternative treatments.



Can estradiol cause hair loss?

Estradiol can cause both hair loss and unwanted hair growth. Tell your healthcare professional if these adverse effects are severe or do not go away with time.



How long can estradiol be taken?

Taking estradiol is associated with several serious health risks. This medication is generally prescribed at the lowest dose that relieves menopausal symptoms, and it is used for the shortest possible time. Your doctor will review the need to continue treatment every 3-6 months. You should work with your doctor to decide how long you should stay on this medication.



Can you quit estradiol cold turkey?

Yes, you can stop taking estradiol cold turkey (suddenly) and do just fine. However, you may have a return of your menopause symptoms when you stop taking hormone replacement therapy.



Can you take HRT on alternate days?

It is not recommended that you take hormone replacement therapy on alternate days, as this can cause fluctuations in your blood hormone levels.



What is the price of estradiol without insurance?

Without insurance, estradiol can be as high as $87.65, but with a free BuzzRx prescription discount coupon, you could pay as low as $35.81 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price and enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions of estradiol like Estrace, Yuvafem, Vivelle-Dot, EstroGel, and Alora. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.



What is the price of estradiol with insurance?

Ask your pharmacist or insurance provider for your copay price on estradiol—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins. You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for estradiol. When using the BuzzRx lookup tool to find the price of your medication, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.