Medically Reviewed by Harshi Dhingra, M.D.

Last Reviewed: Jun 28, 2022

Pharmacist Tips


Nexium (esomeprazole) tips from pharmacists

  • Take Nexium with a glass of water at least 1 hour before a meal.

  • Nexium capsules are delayed-release formulations (this ensures the medicine is released in the intestines and is not destroyed by the stomach acid). Take the capsules whole with a glass of water. If you are using Nexium granules, mix the powder in water or applesauce and swallow immediately without chewing.

  • Nexium can interact with other medications, including prescription and non-prescription medicines, herbal products, and dietary supplements. Be sure to give your doctor a complete list of your medicines.