Oxcarbazepine

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 12, 2023

Side Effects


Oxcarbazepine (Trileptal) Side Effects

Possible side effects of oxcarbazepine are listed below. Call your doctor for medical advice if they are severe or persist after a few days.

  • Rapid, repeated, uncontrolled eye movements
  • Double vision
  • Dizziness
  • Drowsiness
  • Tiredness
  • Gastrointestinal symptoms such as heartburn, stomach pain, nausea, vomiting, diarrhea, constipation, loss of appetite, changes in taste
  • Dry mouth
  • Thirst
  • Headache
  • Weight gain
  • Increased sweating
  • Shakiness, difficulty with coordination, falls, slow movements
  • Forgetfulness, difficulty concentrating, speech problems
  • Back, leg, or arm pain
  • Muscle pain, weakness, or tightness
  • Vaginal redness, itching, swelling, irritation, burning, or discharge

Oxcarbazepine can also cause a more serious drug reaction. Tell your doctor right away or seek emergency medical attention if you develop an unusual or allergic reaction such as:

  • New or worsening seizures
  • Skin rash, hives, itching, blistering, shedding, or peeling of skin
  • Swelling of the face, eyes, lips, tongue, throat, hands, lower legs, ankles, or feet
  • Trouble breathing or swallowing
  • Lack of energy, headache, nausea, confusion
  • Mouth sores, fever, unusual tiredness, muscle weakness, muscle aches
  • Systemic symptoms or flu-like symptoms such as fever, chills, sore throat, swollen glands
  • Swelling in the face, neck, underarms, or groin
  • Yellowing of the skin or eyes
  • Unusual bleeding
  • Bloody, cloudy, or painful urination 
  • Increased or decreased urine output

The above list may not include all the potential side effects of oxcarbazepine. Contact your healthcare provider if your side effects are unusual or severe or do not get better over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Oxcarbazepine Overdose: In case of an overdose of oxcarbazepine, call your doctor immediately. You can also call your local poison control center, provincial poison control center, or the national poison control center at 1-800-222-1222. Call 911 or emergency services if a person has collapsed, cannot breathe, has had a seizure, or cannot be awakened.

Source: FDA