Progesterone

Medically Reviewed by HaVy Ngo-Hamilton, Pharm.D.

Last Reviewed: Jun 15, 2022

Pros & Cons


What are the pros and cons of progesterone (Prometrium)?

pros header.svg

  • Available as a generic at a lower price
  • Injection form is available for adults with problems swallowing.
  • Once-daily dosing - good for compliance
  • Provides protection of the uterus for post-menopausal women who are using estrogen-containing medication.


cons header.svg

  • Can cause significant dizziness and drowsiness
  • Progesterone capsules are contraindicated for those with peanut allergy
  • Increases the risk of blood clots, strokes, and certain cancers
  • Not a safe option for people with liver problems