What side effects may I notice from receiving Sirolimus?

Side effects that you should report to your care team as soon as possible:
-Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
-Dry cough, shortness of breath or trouble breathing
-Increase in blood pressure
-Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
-Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
-Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
-Swelling of the ankles, hands, or feet, shortness of breath or trouble breathing, sudden weight gain
-Unusual bruising or bleeding
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Diarrhea
-Headache
-Joint pain
-Nausea
-Stomach pain

This list may not describe all possible side effects for Sirolimus. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.