Do not take this medicine with the following medication:

-didanosine, ddI

This medicine may also interact with the following medications:

-certain antibiotics like amoxicillin, ampicillin
-certain medicines for cancer
-certain medicines for immunosuppression like azathioprine, cyclosporine, mercaptopurine
-chlorpropamide
-probenecid
-thiazide diuretics, like hydrochlorothiazide
-sulfinpyrazone
-warfarin

They need to know if you have any of these conditions:

-kidney disease
-liver disease
-an unusual or allergic reaction to allopurinol, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast feeding

Visit your doctor or healthcare provider for regular checks on your progress. If you are taking this medicine to treat gout, you may not have less frequent attacks at first. Keep taking your medicine regularly and the attacks should get better within 2 to 6 weeks. Drink plenty of water (10 to 12 full glasses a day) while you are taking this medicine. This will help to reduce stomach upset and reduce the risk of getting gout or kidney stones.

Call your doctor or healthcare provider at once if you get a skin rash together with chills, fever, sore throat, or nausea and vomiting, if you have blood in your urine, or difficulty passing urine.

This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your healthcare provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

Do not take vitamin C without asking your doctor or healthcare provider. Too much vitamin C can increase the chance of getting kidney stones.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Alcohol can also increase the chance of stomach problems and increase the amount of uric acid in your blood. Avoid alcoholic drinks.

Keep out of the reach of children.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.