Warnings


What may interact with Bosulif?

-Antacids
-Certain stomach acid blockers
-Grapefruit juice
-Supplements, such as St. John's wort
Other medications may affect the way this medication works. Talk with your care team about all of the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.

What should I tell my health care provider before I take Bosulif

They need to know if you have any of these conditions:
-Diabetes
-Heart disease
-High blood pressure
-Kidney disease
-Liver disease
-An unusual or allergic reaction to bosutinib, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breast-feeding

What should I watch for while using Bosulif?

Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication.
You may need blood work while taking this medication.
This medication may increase your risk to bruise or bleed. Call your care team if you notice any unusual bleeding.
This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy or for 2 weeks after the last dose. A negative pregnancy test is required to before starting this medication. A reliable form of contraception is recommended while taking this medication and for 2 weeks after the last dose. Talk to your care team about reliable forms of contraception.
Do not breast-feed while taking this medication and for 2 weeks after the last dose.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.

Where should I keep my medicine?

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Keep the container tightly closed. Do not throw out the packet in the container. It keeps the medication dry. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.