Do not take this medication with any of the following:
-Avanafil
-Defibrotide
-Itraconazole
This medication may also interact with the following:
-Aspirin
-Certain antibiotics, such as clarithromycin, telithromycin, and rifampin
-Certain antiviral medications for HIV or AIDS, such as atazanavir, indinavir, nelfinavir, ritonavir, and saquinavir
-Certain medications for cholesterol, such as lovastatin and simvastatin
-Certain medications for fungal infections, such as itraconazole, ketoconazole and voriconazole
-Certain medications for seizures, such as carbamazepine, phenobarbital, and phenytoin
-Digoxin
-Opioid medications for pain
-Nefazodone

They need to know if you have any of these conditions:
-Bleeding disorders
-Bleeding in the brain
-Colon polyps
-Having surgery
-History of irregular heartbeat or rhythm
-History of stomach bleeding
-Liver disease
-Lung or breathing disease (asthma, COPD)
-Severe injury
-Sleep apnea
-Stomach ulcer
-Stroke or transient ischemic attack
-Take medications that treat or prevent blood clots
-An unusual or allergic reaction to ticagrelor, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breast-feeding

Visit your care team for regular checks on your progress. Your condition will be monitored carefully while you are receiving this medication. It is important not to miss any appointments.
This medication may increase your risk to bruise or bleed. Call your care team if you notice any unusual bleeding.
Avoid sports and activities that might cause injury while you are using this medication. Severe falls or injuries can cause unseen bleeding. Be careful when using sharp tools or knives. Consider using an electric razor. Take special care brushing or flossing your teeth. Report any injuries, bruising, or red spots on the skin to your care team.
If you are going to need surgery or other procedure, tell your care team that you are taking this medication.
Tell your dentist and dental surgeon that you are taking this medication. You should not have major dental surgery while on this medication. See your dentist to have a dental exam and fix any dental problems before starting this medication. Take good care of your teeth while on this medication. Make sure to see your dentist for regular follow-up appointments.
Take aspirin every day with this medication. Do not take more than 100 mg of aspirin per day.
Wear a medical ID bracelet or chain. Carry a card that describes your condition. List the medications and doses you take on the card.

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Keep the container tightly closed.
Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.