Side Effects


What side effects may I notice from receiving Depakote ER?

Side effects that you should report to your care team as soon as possible:
-Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
-High ammonia level—unusual weakness or fatigue, confusion, loss of appetite, nausea, vomiting, seizures
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
-Low body temperature, drowsiness, confusion
-Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
-Rash, fever, and swollen lymph nodes
-Redness, blistering, peeling, or loosening of the skin, including inside the mouth
-Thoughts of suicide or self-harm, worsening mood, feelings of depression
-Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Change in vision
-Dizziness
-Drowsiness
-Hair loss
-Headache
-Nausea
-Tremors or shaking
-Weight gain

This list may not describe all possible side effects for Depakote ER. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA