Common Questions about Diphenoxylate-Atropine

Is diphenoxylate-atropine an opioid?

Diphenoxylate, which is one of the active ingredients in Lomotil, is an opioid. It is the same class of drugs as morphine, oxycodone, hydrocodone, and fentanyl. Small doses of diphenoxylate and atropine are used to treat diarrhea. This medicine does not have pain-relieving effects like other opioids. However, like all opioids, there is a risk of abuse and addiction. Diphenoxylate and atropine is therefore classified as a Schedule V controlled substance (other opioids like morphine are Schedule II drugs).

Is diphenoxylate-atropine better than Imodium?

Both diphenoxylate and atropine (Lomotil) and loperamide (Imodium) can effectively treat diarrhea. However, the main difference between these anti-diarrheals is that Imodium is available over-the-counter while Lomotil is a prescription medication and controlled substance.

How many Lomotil tablets can I take in a day?

The maximum dose of diphenoxylate and atropine (Lomotil) is two tablets four times a day. This is a total of 8 tablets in a day. Each tablet contains diphenoxylate 2.5 mg. The diphenoxylate maximum daily dose is therefore 20 mg.

What happens if you take too much Lomotil?

Taking too much diphenoxylate and atropine (Lomotil) can lead to serious and potentially life-threatening complications including respiratory depression, coma, and death. Seek emergency medical care if you or a loved one has overdosed on this medicine.

Can you become addicted to Lomotil?

Lomotil is a Schedule V controlled substance, meaning it has a lower potential for abuse and addiction than other opioids, many of which are Schedule II drugs. However, long-term use of Lomotil can lead to opioid withdrawal symptoms if the medicine is stopped suddenly. Seek medical help if you experience symptoms like anxiety, restlessness, irritability, sweating, chills, or widening of the pupils after stopping Lomotil after prolonged use. 

What is the price of Lomotil without insurance?

Without insurance, Lomotil can be as high as $35.24, but with a free BuzzRx prescription discount coupon, you could pay as low as $11.66 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.

What is the price of Lomotil with insurance?

Ask your pharmacist or insurance provider for your copay price on Lomotil—copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for Lomotil. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.