Do not take this medication with any of the following:
-Certain contrast medications given before X-rays, CT scans, MRI, or other procedures
-Dofetilide
This medication may also interact with the following:
-Acetazolamide
-Alcohol
-Certain antivirals for HIV or hepatitis
-Certain medications for blood pressure, heart disease, irregular heart beat
-Cimetidine
-Dichlorphenamide
-Digoxin
-Diuretics
-Estrogen and progestin hormones
-Glycopyrrolate
-Isoniazid
-Lamotrigine
-Memantine
-Methazolamide
-Metoclopramide
-Midodrine
-Niacin
-Phenothiazines, such as chlorpromazine, mesoridazine, prochlorperazine, thioridazine
-Phenytoin
-Ranolazine
-Steroid medications, such as prednisone or cortisone
-Stimulant medications for attention disorders, weight loss, or to stay awake
-Thyroid medications
-Topiramate
-Trospium
-Vandetanib
-Zonisamide

They need to know if you have any of these conditions:
-Dehydration
-Frequently drink alcohol
-Gallbladder disease
-Heart disease
-Heart failure
-High levels of triglycerides in the blood
-History of diabetic ketoacidosis (DKA)
-History of pancreatitis
-Kidney disease
-Liver disease
-Low levels of vitamin B12 in your blood
-Low red blood cell levels
-Polycystic ovary syndrome
-Previous swelling of the tongue, face, or lips with trouble breathing, trouble swallowing, hoarseness, or tightening of the throat
-Serious infection or injury
-Type 1 diabetes
-An unusual or allergic reaction to metformin, sitagliptin, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breastfeeding

Visit your care team for regular checks on your progress.
A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.
Know the symptoms of low blood sugar and know how to treat it. Always carry a source of quick sugar with you. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink if your blood sugar is too low and you are unable to care for yourself. Get medical help at once.
Tell your care team if you have high blood sugar. Your medication dose may change if your body is under stress. Some types of stress that may affect your blood sugar include fever, infection, and surgery.
Do not skip meals. Ask your care team if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.
This medication may cause you to ovulate, which may increase your chances of becoming pregnant. Talk with your care team about contraception while you are taking this medication. Contact your care team if you think you might be pregnant.
If you are going to need surgery, an MRI, CT scan, or other procedure, tell your care team that you are taking this medication. You may need to stop taking this medication before the procedure.
Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medication and dosage times.
This medication may cause a decrease in folic acid and vitamin B12. You should make sure that you get enough vitamins while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.

Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date.