Lansoprazole

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Sep 06, 2022

Uses


Lansoprazole Uses

Lansoprazole is used to treat conditions in which there is too much acid secretion in the stomach. It is used to relieve symptoms of gastroesophageal reflux disease (GERD) and ulcers in the stomach and duodenum. It is administered concomitantly with two other medicines as part of triple therapy for Helicobacter pylori (H. pylori) infections. Lansoprazole is also prescribed to people with certain other conditions in which there is excess stomach acid production, such as Zollinger-Ellison syndrome.

There may be other uses of lansoprazole. Your healthcare professionals or pharmacist can give you further lansoprazole drug information.

Lansoprazole Mechanism of Action

Lansoprazole works by decreasing the amount of acid made in the stomach and increasing gastric pH.

Lansoprazole Doses

Lansoprazole is available as 15 mg and 30 mg orally disintegrating tablets and 15 mg and 30 mg delayed-release capsules. The dosage of lansoprazole depends on the condition being treated. Usual doses in adults are as follows:

  • Short-term treatment of stomach ulcer: 30 mg once daily for up to 8 weeks.
  • Short-term treatment of duodenal ulcers: 15 mg once daily for 4 weeks.
  • Maintenance therapy following initial therapy for duodenal ulcer: 15 mg once daily.
  • H. pylori (as part of triple therapy): 30 mg twice daily for 10-14 days.
  • NSAID-associated gastric ulcer: 30 mg once daily for up to 8 weeks.
  • Risk reduction of NSAID-associated ulcer: 15 mg once daily for up to 12 weeks.
  • Short-term treatment of symptomatic GERD (acid reflux): 15 mg once daily for up to 8 weeks.
  • Short-term treatment of erosive esophagitis: 30 mg once daily for up to 8 weeks.
  • OTC lansoprazole to treat frequent heartburn: 15 mg once daily for 14 days.

Pediatric doses of lansoprazole depend on the child’s weight and the condition being treated.