-Alcohol
-Antihistamines for allergy, cough, and cold
-Antiviral medications for HIV or AIDS
-Atropine
-Certain antibiotics, such as erythromycin, clarithromycin
-Certain medications for anxiety or sleep
-Certain medications for bladder problems, such as oxybutynin, tolterodine
-Certain medications for depression, such as amitriptyline, fluoxetine, sertraline
-Certain medications for fungal infections, such as ketoconazole and itraconazole
-Certain medications for Parkinson disease, such as benztropine, trihexyphenidyl
-Certain medications for seizures, such as carbamazepine, phenobarbital, phenytoin, primidone
-Certain medications for stomach problems, such as dicyclomine, hyoscyamine
-Certain medications for travel sickness, such as scopolamine
-General anesthetics, such as halothane, isoflurane, methoxyflurane, propofol
-Ipratropium
-Local anesthetics, such as lidocaine, pramoxine, tetracaine
-MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, Parnate
-Medications that relax muscles for surgery
-Other medications with acetaminophen
-Other opioid medications for pain or cough
-Phenothiazines, such as chlorpromazine, mesoridazine, prochlorperazine, thioridazine
-Rifampin

They need to know if you have any of these conditions:
-Brain tumor
-Frequently drink alcohol
-Head injury
-Heart disease
-Kidney disease
-Liver disease
-Low adrenal gland function
-Lung or breathing disease, such as asthma or COPD
-Seizures
-Stomach or intestine problems
-Substance use disorder
-Taken an MAOI, such as Marplan, Nardil, or Parnate in the last 14 days
-An unusual or allergic reaction to acetaminophen, hydrocodone, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breastfeeding

Tell your care team if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to this medication. Tolerance means that you will need a higher dose of the medication for pain relief. Tolerance is normal and is expected if you take this medication for a long time.
Taking this medication with other substances that cause drowsiness, such as alcohol, benzodiazepines, or other opioids can cause serious side effects. Give your care team a list of all medications you use. They will tell you how much medication to take. Do not take more medication than directed. Call emergency services if you have problems breathing or staying awake.
Children may be at higher risk for side effects. Stop giving this medication and call emergency services right away if your child has slow or noisy breathing, has confusion, is unusually sleepy, or not able to wake up.
Long term use of this medication may cause your brain and body to depend on it. This can happen even when used as directed by your care team. You and your care team will work together to determine how long you will need to take this medication. If your care team wants you to stop this medication, the dose will be slowly lowered over time to reduce the risk of side effects.
Naloxone is an emergency medication used for an opioid overdose. An overdose can happen if you take too much of an opioid. It can also happen if an opioid is taken with some other medications or substances such as alcohol. Know the symptoms of an overdose, such as trouble breathing, unusually tired or sleepy, or not being able to respond or wake up. Make sure to tell caregivers and close contacts where your naloxone is stored. Make sure they know how to use it. After naloxone is given, the person giving it must call emergency services. Naloxone is a temporary treatment. Repeat doses may be needed.
This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
Do not take other medications that contain acetaminophen with this medication. Many non-prescription medications contain acetaminophen. Always read labels carefully. If you have questions, ask your care team.
If you take too much acetaminophen, get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.
This medication will cause constipation. If you do not have a bowel movement for 3 days, call your care team.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe.
Talk to your care team if you may be pregnant. Prolonged use of this medication during pregnancy can cause temporary withdrawal in a newborn.
Talk to your care team before breastfeeding. Changes to your treatment plan may be needed. If you breastfeed while taking this medication, seek medical care right away if you notice the child has slow or noisy breathing, is unusually sleepy or not able to wake up, or is limp.
Long-term use of this medication may cause infertility. Talk to your care team if you are concerned about your fertility.

Keep out of the reach of children and pets. This medication can be abused. Keep your medication in a safe place to protect it from theft. Do not share this medication with anyone. Selling or giving away this medication is dangerous and against the law.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).
This medication may cause harm and death if it is taken by other adults, children, or pets. It is important to get rid of the medication as soon as you no longer need it or it is expired. You can do this in two ways:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, flush it down the toilet.