Do not take this medication with any of the following:
-Antidiarrheal medications, such as diphenoxylate or loperamide
-Crofelemer
-Fluvoxamine
-Viloxazine
This medication may also interact with the following:
-Certain antibiotics, such as ciprofloxacin, enoxacin, clarithromycin, erythromycin, troleandomycin
-Certain antivirals for HIV or hepatitis
-Cimetidine
-Hydralazine
-Isoniazid, INH
-Medications for fungal infections, such as ketoconazole, itraconazole, voriconazole
-Opioid medications for pain
-Procainamide

They need to know if you have any of these conditions:
-Blood clotting disorder
-Blood flow problems to your bowels, such as ischemic colitis
-Constipation
-Diverticulitis
-History of bowel blockage
-Inflammatory bowel disease, such as Crohn disease or ulcerative colitis
-Liver disease
-An unusual or allergic reaction to alosetron, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breastfeeding

If you get constipated, serious side effects may occur. Do not take this medication if you are constipated. If you have constipation, new or worsening abdominal pain, bloody diarrhea, or blood in the stool, immediately stop taking this medication and contact your care team.

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.