Warnings


What may interact with Ofev?

-Aspirin and aspirin-like medications
-Certain antibiotics, such as erythromycin or clarithromycin
-Certain medications for seizures, such as carbamazepine, phenobarbital, or phenytoin
-Certain medications that treat or prevent blood clots, such as warfarin, enoxaparin, dalteparin, apixaban, dabigatran, and rivaroxaban
-Ketoconazole
-Rifampin
-St. John's Wort

What should I tell my health care provider before I take Ofev

They need to know if you have any of these conditions:
-Bleeding disorders or family history of bleeding disorders
-Heart disease
-History of blood clots
-Liver disease
-Protein in your urine
-Recent surgery
-Stomach or intestinal problems
-Tobacco use
-An unusual or allergic reaction to nintedanib, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breastfeeding

What should I watch for while using Ofev?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. You may need blood work done while you are taking this medication.
Drink plenty of fluids while taking this medication. Check with your care team if you have diarrhea, nausea, and vomiting. The loss of too much body fluid may make it dangerous for you to take this medication.
If you smoke, tell your care team if you notice this medication is not working well for you. Talk to your care team if you decide to stop smoking.
This medication may increase your risk to bruise or bleed. Call your care team if you notice any unusual bleeding.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy and for 3 months after stopping it. A negative pregnancy test is required before starting this medication. If you become pregnant, miss a menstrual cycle, or stop using contraception, stop taking this medication. Call your care team.

Where should I keep my medicine?

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Avoid exposure to extreme heat. Protect from moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.