What side effects may I notice from receiving Orilissa?

Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
-Thoughts of suicide or self-harm, worsening mood, feelings of depression
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Anxiety, nervousness
-Headache
-Hot flashes
-Joint pain
-Nausea
-Trouble sleeping

This list may not describe all possible side effects for Orilissa. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.