Siklos
Warnings
What may interact with Siklos?
-Antivirals for HIV, such as didanosine or stavudine
-Live virus vaccines
What should I tell my health care provider before I take Siklos
They need to know if you have any of these conditions:
-Gout or high levels of uric acid in your blood
-HIV or AIDS
-Kidney disease or on hemodialysis
-Leg wounds or ulcers
-Liver disease
-Prior or current interferon therapy
-Recent or ongoing radiation
-Recent or upcoming vaccine
-Use a continuous glucose monitor (CGM)
-An unusual or allergic reaction to hydroxyurea, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breastfeeding
What should I watch for while using Siklos?
Visit your care team for regular checks on your progress. Report any side effects. Continue your course of treatment even if you have side effects unless your care team tells you to stop.
You may need blood work done while you are taking this medication.
This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Talk to your care team about your vaccination history. Some vaccines are not recommended in people taking this medication. Your care team can help you decide which vaccines are safe for you.
Talk to your care team about your risk of cancer. You may be more at risk for certain types of cancer if you take this medication. To lower your risk of skin cancer, keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and sunscreen. Do not use sun lamps, tanning beds, or tanning booths.
If you wear a continuous glucose monitor (CGM), this medication may affect your sensor blood sugar (glucose) results. Talk to your care team about whether it is safe to use your CGM to dose insulin.
Talk to your care team if you or your partner may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 6 months after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 6 months after the last dose. Your care team can help you find the option that works for you.
Do not handle this medication if you may be or could become pregnant.
If your partner can get pregnant, use a condom during sex while taking this medication and for at least 1 year the last dose.
Talk to your care team before breastfeeding. Changes to your treatment plan may be needed.
Do not handle this medication if you are breastfeeding.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
Where should I keep my medicine?
Keep out of the reach of children and pets.
Store between 20 and 25 degrees C (68 and 77 degrees F). Keep the container tightly closed. Store any broken or half tablets in the original container. Use broken or half tablets within 3 months. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.
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