Do not take this medicine with any of the following medications:

-ciprofloxacin
-fluvoxamine
-narcotic medicines for cough
-thiabendazole
-viloxazine
This medicine may also interact with the following medications:

-acyclovir
-alcohol
-antihistamines for allergy, cough, and cold
-baclofen
-birth control pills
-certain medicines for anxiety or sleep
-certain medicines for blood pressure, heart disease, irregular heartbeat like amiodarone, mexiletine, propafenone, verapamil
-certain medicines for depression like amitriptyline, fluoxetine, sertraline
-certain medicines for seizures like phenobarbital, primidone
-cimetidine
-clonidine
-famotidine
-guanfacine
-general anesthetics like halothane, isoflurane, methoxyflurane, propofol
-medicines for sleep
-medicines that relax muscles for surgery
-methyldopa
-narcotic medicines for pain
-phenothiazines like chlorpromazine, prochlorperazine, thioridazine
-ticlopidine
-zileuton

They need to know if you have any of these conditions:

-kidney disease
-liver disease
-low blood pressure
-mental health disease
-an unusual or allergic reaction to tizanidine, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand up or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effects of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your health care provider if the problem does not go away or is severe.

Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:

-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, take the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.