Warnings


What may interact with Twirla?

Do not take this medication with the following:
-Dasabuvir; ombitasvir; paritaprevir; ritonavir
-Ombitasvir; paritaprevir; ritonavir
This medication may also interact with the following:
-Acetaminophen
-Antibiotics or medications for infections, especially rifampin, rifabutin, rifapentine, and possibly penicillins or tetracyclines
-Aprepitant or fosaprepitant
-Armodafinil
-Ascorbic acid (vitamin C)
-Barbiturate medications, such as phenobarbital or primidone
-Bosentan
-Certain antiviral medications for hepatitis, HIV or AIDS
-Certain medications for cancer treatment
-Certain medications for seizures, such as carbamazepine, clobazam, felbamate, lamotrigine, oxcarbazepine, phenytoin, rufinamide, topiramate
-Certain medications for treating high cholesterol
-Cyclosporine
-Dantrolene
-Elagolix
-Flibanserin
-Grapefruit juice
-Lesinurad
-Medications for diabetes
-Medications to treat fungal infections, such as griseofulvin, miconazole, fluconazole, ketoconazole, itraconazole, posaconazole or voriconazole
-Mifepristone
-Mitotane
-Modafinil
-Morphine
-Mycophenolate
-St. John's Wort
-Tamoxifen
-Temazepam
-Theophylline or aminophylline
-Thyroid hormones
-Tizanidine
-Tranexamic acid
-Ulipristal
-Warfarin

What should I tell my health care provider before I take Twirla

They need to know if you have any of these conditions:
-Abnormal vaginal bleeding
-Blood vessel disease or blood clots
-Breast, cervical, endometrial, ovarian, liver, or uterine cancer
-Diabetes
-Gallbladder disease
-Having surgery
-Heart disease or recent heart attack
-High blood pressure
-High cholesterol or triglycerides
-History of irregular heartbeat or heart valve problems
-Kidney disease
-Liver disease
-Migraine headaches
-Protein C deficiency
-Protein S deficiency
-Recently had a baby, miscarriage, or abortion
-Stroke
-Systemic lupus erythematosus (SLE)
-Tobacco use
-An unusual or allergic reaction to estrogens, progestins, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breast-feeding

What should I watch for while using Twirla?

Visit your care team for regular checks on your progress. You will need a regular breast and pelvic exam and Pap smear while on this medication.
If you have any reason to think you are pregnant, stop using this medication right away and contact your care team.
If you are using this medication for hormone-related problems, it may take several cycles of use to see improvement in your condition.
Smoking tobacco increases the risk of getting a blood clot or having a stroke while you are taking this medication, especially if you are older than 35 years.
This medication can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your care team if you feel you are retaining fluid.
This medication can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.Tenderness, swelling, or minor bleeding of the gums may occur. Talk to your dentist if this happens. Brushing and flossing your teeth regularly may reduce the risk of side effects. Visit your dentist on a regular basis. Tell your dentist about any medications you are taking. If you are going to have elective surgery or an MRI, you may need to stop using this medication before the surgery or MRI. Consult your care team for advice.
Using this medication does not protect you or your partner against HIV or other sexually transmitted infections (STIs).

Where should I keep my medicine?

Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep the patch in its pouch until time of use. Throw away any unused medication after the expiration date.
Dispose of used patches properly. Since a used patch may still contain active hormones, fold the patch in half so that it sticks to itself prior to disposal. Throw away in a place where children or pets cannot reach.