-Bosentan
-Certain antibiotics, such as erythromycin or clarithromycin
-Certain antivirals for HIV or hepatitis
-Certain medications for fungal infections, such as ketoconazole, itraconazole, posaconazole
-Certain medications for seizures, such as carbamazepine, phenobarbital, phenytoin
-Diltiazem
-Efavirenz
-Grapefruit juice
-Modafinil
-Rifampin
-Verapamil

They need to know if you have any of these conditions:
-Blood clots
-Diarrhea
-Infection
-Kidney disease
-Liver disease
-Low white blood cell counts
-Lung disease
-An unusual or allergic reaction to abemaciclib, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breastfeeding

Your condition will be monitored carefully while you are receiving this medication. You may need blood work while taking this medication.
This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.
This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Avoid taking medications that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your care team. These medications may hide a fever.
Be careful brushing or flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medication.
Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 3 weeks after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 3 weeks after the last dose. Your care team can help you find the option that works for you.
Do not breastfeed while taking this medication and for 3 weeks after the last dose.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.