Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 01, 2022

Common Questions


Common Questions about Xyzal (levocetirizine) 


Does Xyzal make you sleepy?

Xyzal can occasionally cause drowsiness in some people, but not everyone. If this is the case, try taking the medicine in the evening before bed. 



What is the difference between Zyrtec and Xyzal?

Both Xyzal (levocetirizine) and Zyrtec (cetirizine) are chemically similar antihistamines. They are both effective over-the-counter medicines for allergy relief. However, Zyrtec, a second-generation antihistamine, is more likely to reach the brain and cause drowsiness than Xyzal, a third-generation antihistamine. Also, a Xyzal tablet is nearly half the size of a Zyrtec tablet.



How fast does Xyzal kick in?
Xyzal starts working pretty quickly, and you should get relief from allergy symptoms within an hour. This medication can help prevent allergy symptoms when taken for more than two days.


Is it okay to take Xyzal on an empty stomach?
Yes, you can take Xyzal with or without food. Gastrointestinal side effects like nausea, vomiting, diarrhea and stomach pain are very rare with this medication.


Can I take Xyzal and other allergy medications together?
You should not take two allergy medicines together without talking to a healthcare professional who can provide medical advice. Sometimes, doctors prescribe Xyzal with another allergy medicine that works differently. For example, Nasonex is a corticosteroid with anti-inflammatory action.


What dosages are available for Xyzal?

Xyzal is available in the following strengths: 5 mg tablets & 2.5mg/5 mL oral solution. This drug is available in the following forms: tablet and oral solution. Make sure to follow your prescription regimen according to your doctor’s instructions.



What is the price of Xyzal without insurance?

Without insurance, Xyzal can be as high as $97.91 (generic), but with a free BuzzRx prescription discount coupon, you could pay as low as $12.78 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not. 



What is the price of Xyzal with insurance?

Ask your pharmacist or insurance provider for your copay price on Xyzal—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for Xyzal. When using the BuzzRx lookup tool to find the price of your medication, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.