Warnings


What may interact with ZEPOSIA?

Do not take this medicine with any of the following medications:

-linezolid
-MAOIs like Azilect, Carbex, Eldepryl, Marplan, Nardil, Parnate, and Xadago
This medicine may also interact with the following medications:

-certain medicines for blood pressure, heart disease, irregular heart beat
-certain medicines for depression, anxiety, or psychotic disorders
-gemfibrozil
-live virus vaccines
-medicines that lower your chance of fighting infection
-other medicines that prolong the QT interval (abnormal heart rhythm)
-narcotic medicines for pain
-pseudoephedrine
-rifampin
-stimulant medicines for attention disorders, weight loss, or staying awake
-tyramine

What should I tell my health care provider before I take ZEPOSIA?

They need to know if you have any of these conditions:

-diabetes
-eye disease, such as uveitis
-heart disease
-high blood pressure
-immune system problems
-infection especially a viral infection such as chickenpox, cold sores, or herpes
-irregular heartbeat or rhythm
-liver disease
-low blood counts (white cells, platelets, or red blood cells)
-recent or upcoming vaccine
-skin cancer/melanoma
-sleep apnea
-stroke or transient ischemic attack
-an unusual or allergic reaction to ozanimod, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using ZEPOSIA?


Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.

You may need blood work while you are taking this medicine.

Foods that contain very high amounts of tyramine, such as aged, fermented, cured, smoked and pickled foods, should be avoided while taking this medicine. The combination may cause a dangerous rise in blood pressure. Ask your health care provider for a complete listing of foods and beverages that are high in tyramine. If you consume a food or beverage very rich in tyramine and do not feel well soon after eating, contact your health care provider.

Tell your health care provider right away if you have any change in your eyesight.

This medicine may increase your risk of getting an infection. Call your health care provider for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and sunscreen. Do not use sun lamps or tanning beds/booths.

Do not become pregnant while taking this medicine or for 3 months after stopping it. Women should inform their health care provider if they wish to become pregnant or think they might be pregnant. There is potential for serious harm to an unborn child. Talk to your health care provider for more information.

If you stop taking this medicine for MS, your symptoms may get worse. You may have more weakness, trouble using your arms or legs, or changes in balance. Talk to your health care provider right away if your symptoms get worse.

Where should I keep my medicine?

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:

-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, take the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.